There are increasing data showing that tumor volume is one of the most promising factors, but this is not incorporated into the current TNM system because the measurement of this criterion is not globally available and consensus on the cutoff value has yet to be attained. Quynh Thu Le reports a grant from Amgen to Stanford University to conduct a long-term follow-up study of patients enrolled in past trials.
Author manuscript; available in PMC Aug 1. Keywords: nasopharyngeal cancer, prognostication, TNM staging system. Ho JHC. Stage classification of nasopharyngeal carcinoma: a review. In: de The G, Ito Y, editors. Nasopharyngeal Carcinoma: Etiology and Control. Int J Cancer. Sobin LH, Wittekind C, editors. Clin Oncol R Coll Radiol ; 16 — Retropharyngeal lymph node metastasis in nasopharyngeal carcinoma detected by magnetic resonance imaging: prognostic value and staging categories.
Impact of intensity-modulated radiotherapy on nasopharyngeal carcinoma: validation of the 7th edition AJCC staging system. Oral Oncol. Prognostic value and staging categories of anatomic masticator space involvement in nasopharyngeal carcinoma: a study of cases with MR imaging. Prognostic value of subclassification using MRI in the T4 classification nasopharyngeal carcinoma intensity-modulated radiotherapy treatment.
A new T classification based on masticator space involvement in nasopharyngeal carcinoma: a study of cases with magnetic resonance imaging. BMC Cancer. Prognostic value of grading masticator space involvement in nasopharyngeal carcinoma according to MR imaging findings. Should all nasopharyngeal carcinoma with masticator space involvement be staged as T4?
The prognosis of nasopharyngeal carcinoma involving masticatory muscles: a retrospective analysis for revising T subclassifications.
Medicine Baltimore ; 94 :e Prevertebral muscle involvement in nasopharyngeal carcinoma. The prognostic influence of prevertebral space involvement in nasopharyngeal carcinoma. Clin Otolaryngol. Prognostic value of prevertebral space involvement in nasopharyngeal carcinoma based on intensity-modulated radiotherapy.
Imaging-based nodal classification for evaluation of neck metastatic adenopathy. N-staging by magnetic resonance imaging for patients with nasopharyngeal carcinoma: pattern of nodal involvement by radiological levels. Radiother Oncol. Proposed lymph node staging system using the international consensus guidelines for lymph node levels is predictive for nasopharyngeal carcinoma patients from endemic areas treated with intensity modulated radiation therapy.
A comparison between the Chinese and the 7th edition AJCC staging systems for nasopharyngeal carcinoma. Am J Clin Oncol. Comparison of TNM staging systems for nasopharyngeal carcinoma, and proposal of a new staging system. Br J Cancer. Is replacement of the supraclavicular fossa with the lower level classification based on magnetic resonance imaging beneficial in nasopharyngeal carcinoma?
Clinical outcomes and patterns of failure after intensity-modulated radiotherapy for nasopharyngeal carcinoma. Nasopharyngeal carcinoma treated with reduced-volume intensity-modulated radiation therapy: report on the 3-year outcome of a prospective series.
Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. Peto R, Peto J. Permission applies only to the material and use specified in correspondence. New requests should be made for subsequent use or for other uses of material. To request permission to photocopy, duplicate, republish, or otherwise reuse AJCC material in journals, presentations or course material, follow the instructions below.
For Sixth, Seventh, Eighth Editions please contact bookpermissions springernature. For Fifth Edition please contact the publisher at healthpermissions wolterskluwer. Please note that some items in the manual are reproduced with permission from other rights holders.
If you wish to reproduce any of those items, you must request permission from the original rights holders. This is often possible through www. Identification of the edition in which materials to be reproduced appears. For this new edition, the editorial board worked to increase the level of documentation explaining the reasons for changes and the level of evidence supporting each change.
The Evidence Based Medicine and Statistics Core established a system for quantifying the level of evidence supporting each major staging recommendation see Chapter 2. The level of evidence supporting the staging systems and their ongoing refinement during the publication of the next edition varies among disease sites.
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